Untargeted Metabolomics

Untargeted metabolomics, which is also called discovery metabolomics, involves the comparison of the metabolome identification between the control and test sample group, to identify differences between their metabolite profiles which may be relevant to specific biological conditions.

Experimental workflow Mainly three Steps:

  1. Metabolites Profiling in order to seek the metabolites with statistically significant variations in abundance within a set of treated and control samples;
  2. Determination of metabolite ID, including the chemical structure;
  3. Comprehensions as the last step which makes connections between the identified metabolites and the biological processes.

In the workflow of Untargeted metabolomics, analytical reproducibility is critical for expression profiling work; annotation is a tentative identification based on an accurate mass match to a database or a spectral match to a library; the collected data can be interpreted for biomarker discovery, biological signature/fingerprint selection and pathway mapping. Above are the most important parts in discovery metabolomic research. Technical tam of the Novelgene is experienced in sample preparation, data interpretations. It also can provide you reliable metabolite identification.

With integrated a set of separation, characterization, identification and quantification systems featured with excellent robustness & reproducibility, high and ultra-sensitivity, Novelgene provides reliable, rapid and cost-effective Untargeted Metabolomics as below.

  • Serum Untargeted Metabolomics
  • Urine Untargeted Metabolomics
  • Cerebrospinal Fluid Untargeted Metabolomics
  • Plant Untargeted Metabolomics