Gutmicrobiota Test for life style disease (like Obesity, Diabetes , Hypertension)
HEALTHY HUMAN GUT MICROBIOTA COMPOSITION
Conducted a study where we analyzed fecal samples from 100 healthy individuals to understand the composition of the human gut microbiota. We found that the gut microbiota is primarily composed of five major phyla of bacteria, which are Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria, and Fusobacteria.
Each of these phyla makes up a certain percentage of the overall bacterial population in the gut.
New Research:
Their investigation revealed that food-addicted mice had increased Proteobacteria and decreased Actinobacteria and Blautia. Similar patterns were observed in food-addicted humans.
These findings suggest certain microbiota could protect against food addiction, particularly Blautia, which showed potential benefits in both mice and humans.
The researchers further tested the effects of prebiotics like lactulose and rhamnose, which boost Blautia levels in the gut.
Unhealthy Gut, 10 signs you should not ignore:
- Inability to lose weight: Are you gaining unwanted weight despite trying your best to lose a few kilos? It could be a major sign of gut imbalance. Imbalance of gut microbiota hampers nutrient absorption, disturbs sugar levels, and stores unhealthy fat, causing havoc on weight. This could be a reason why you are unable to lose weight despite an active lifestyle.
- Fluctuation in weight: Your inability to gain weight or unexplained weight loss despite conscious efforts could also be due to a poor gut. The inactivity of healthy gut bacteria has been linked with poor digestion and absorption of essential nutrients. This could lead to malnutrition and trigger unwanted weight loss.
- Trouble in getting restful sleep: A poor gut can impact sleep quality, causing fatigue. Notably, over 90% of the happy chemical serotonin is produced in the gut, gut inflammation or inactivity of good bacteria can hamper its production, affecting your sleep quality and mood.
- Frequent stomach upset: Regular occurrences of gas, bloating, heartburn, constipation, and diarrhea could be major signs that your gut is facing issues in processing food and eliminating waste. These symptoms not only cause discomfort but also hamper your quality of life.”
- Feeling more tired than usual: A study found that most individuals with chronic fatigue also suffered from IBS. So, feeling fatigued more than usual could be a warning sign of gut imbalance and you must seek necessary help to reverse it.
- Constant brain fog: Bouts of brain fog throughout the day could also be linked to our gut health. This is because our gut and brain are connected through neurological pathways, as the former actively sends nutrients and healthy fats to the latter. In case of inadequate nutrients, we may have difficulty concentrating or keeping our thoughts straight, which would take a toll on our productivity.
- Frequent skin flare-ups: A lower concentration of gut-friendly bacteria is said to affect our immune system and overall skin health, triggering conditions such as acne, eczema, and even psoriasis. In fact, acne has been linked with a disorder – small intestinal bacterial overgrowth.
- Intolerance to certain food items: Typically, our gut becomes intolerant to certain foods due to an imbalance of microbiota. This imbalance makes it challenging to digest certain foods like gluten, which you could previously enjoy. It can also trigger symptoms such as nausea, diarrhea, gas, and abdominal pain, hampering the flow of daily life.
- Frequent headaches: Some studies have also found a link between frequent headaches and gastrointestinal disorders. In case you experience nausea and vomiting with frequent migraine episodes you should pay attention to your gut health.
- Autoimmune issues: It’s not known to many that certain harmful strains of bacteria can trigger autoimmune concerns such as type 1 diabetes, thyroid issues, and rheumatoid arthritis. So, any symptoms of the same should not be taken lightly.
Below Figure is created to understand the diseases linked to DYSBIOSIS (Imbalance of bacterial community in human Gut).
Why Choose Novelgene:
- Unique In-house Protocols: Novelgene has developed proprietary methodologies for gut microbiota analysis, starting from stool sample collection to final analysis.
- Careful Sample Collection: Extra care is taken during stool sample collection, with controlled temperature management and transportation in specially designed boxes.
- Temperature Control & Processing: Ambient temperature is maintained during transportation, and samples are immediately processed for DNA isolation, preserving natural microbial diversity.
- Optimized Procedures: The entire procedure, from DNA isolation to sequencing, has been optimized for speed, making it faster than other labs in India.
- Advanced Markers and Tools: Novelgene has developed specialized markers and tools to identify potential metabolites produced by the microbial community and analyze microbiota ratios, which may be linked to neurological disorders.
- Comprehensive Microbiota Reports: 2-3 week
- GUT-Microbiome Diversity Score
- F/B Ratio: Firmicutes and Bacteroidetes are two major classes of Bacteria, dominant in the human gut microbiome. The Firmicutes to Bacteroidetes ratio (F/B ) correlates with the balance or imbalance in the gut microbiome. An ideal F/B ratio would lie between 0.5 to 1.2. An imbalance may indicate a risk for metabolic disorders.
- Know your most abundant bacteria, Pathogenic bacteria, opportunistic bacteria, probiotic bacteria etc with their %abundance
- Microbiome-based metabolic indicators: Butyrate, Gas, inflammatory and non-inflammatory producers.
- Finding on the basis of DYSBIOSIS and Summary Reports.
- Phase I: GUT-REBOOT (Initially 3-4 weeks under the supervision of gastroenterologist and nutritionist)
- Phase 2: GUT-REBUILD (Next 3-4 weeks under the supervision of gastroenterologist and nutritionist)
- Phase 3: GUT-RETAIN (Next 4-6 weeks under the supervision of gastroenterologist and nutritionist)
Samples Requirement: STOOL SAMPLE ONLY (samples collection will be taken care by Novelgene Wellness Team only)
